Aberrant Cell Cycle Regulation in Cervical Carcinoma
نویسندگان
چکیده
منابع مشابه
Aberrant Cell Cycle Regulation in Cervical Carcinoma
Carcinoma of the uterine cervix is one of the most common malignancies among women worldwide. Human papillomaviruses (HPV) have been identified as the major etiological factor in cervical carcinogenesis. However, the time lag between HPV infection and the diagnosis of cancer indicates that multiple steps, as well as multiple factors, may be necessary for the development of cervical cancer. The ...
متن کاملAberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cells by Deregulating Expression of G1/S Cell Cycle Proteins
Histone deacetylase 2 (HDAC2) is crucial for embryonic development, affects cytokine signaling relevant for immune responses and is often significantly overexpressed in solid tumors; but little is known about its role in human hepatocellular carcinoma (HCC). In this study, we showed that targeted-disruption of HDAC2 resulted in reduction of both tumor cell growth and de novo DNA synthesis in He...
متن کاملThe Impact of Hyperthermia in Radiosensitivity of Human Cervical Carcinoma Cell Line HeLa
Introduction: The objective of this work was to investigate the therapeutic effect of a combination of hyperthermia at 43oC exposured for 20, 40, 60 min with 6MeV electron beams at different radiation doses (2, 4, 6 Gy) compared to radiation alone. Materials and Methods: In this in vitro study, HeLa cells were exposed to either: 6MeV electron beams at diffe...
متن کاملRate of Occult Cervical Lymph Node Involvement in Supraglottic Squamous Cell Carcinoma
Introduction: To assess the rate of cervical lymph node involvement in patients with supraglottic squamous cell carcinoma (SCC) with no lymph node in clinical assessments and radiological studies. Materials and Methods: Fifty-six patients who underwent elective dissection of the cervical lymph node of the second through fourth level were enrolled, and pathologic evaluation of the dissected lymp...
متن کاملAberrant regulation of Wnt signaling in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most lethal malignancies in the world. Several signaling pathways, including the wingless/int-1 (Wnt) signaling pathway, have been shown to be commonly activated in HCC. The Wnt signaling pathway can be triggered via both catenin β1 (CTNNB1)-dependent (also known as "canonical") and CTNNB1-independent (often referred to as "non-canonical") pathways. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Yonsei Medical Journal
سال: 2005
ISSN: 0513-5796
DOI: 10.3349/ymj.2005.46.5.597